Description

Buy Adipotide Peptide 5mg & 10mg For Sale Online

Adipotide, also known as FTPp, is a synthetic fat-targeting peptide designed to trigger apoptosis (programmed cell death) in white adipose tissue (WAT) vasculature. Extensively studied in preclinical models for its fat-reducing and anti-obesity effects, Adipotide offers a revolutionary approach to metabolic and obesity research.

Available in 5mg and 10mg lyophilized vials, this high-purity peptide is for research use only, intended for laboratory testing related to fat metabolism, weight loss, and vascular targeting strategies.

Chemical & Physical Properties:

• Product Name: Adipotide (FTPp)

• Synonyms: Prohibitin-Targeting Peptide, FTPp

• Form: Lyophilized powder

• Purity: ≥98% (HPLC Verified)

• Available Sizes: 5mg / 10mg per vial

• Molecular Formula: C60H91N17O13S

• Molecular Weight: ~1289.5 g/mol

• Sequence: CKGGRAKDC-GG-D(KLAKLAK)2

• Storage Conditions: Store at -20°C dry. After reconstitution, refrigerate at 2–8°C and use within 30 days.

• Solubility: Soluble in sterile water or acetic acid + PBS buffer

Mechanism of Action:

Adipotide is a dual-function peptide consisting of two components:

1. Targeting Domain (CKGGRAKDC):
   Binds selectively to prohibitin, a mitochondrial membrane protein overexpressed in the endothelial cells of white adipose tissue vasculature.

2. Effector Domain (D(KLAKLAK)₂):
   This cytotoxic sequence disrupts mitochondrial membranes, leading to apoptosis of targeted endothelial cells and subsequent fat cell degradation due to nutrient supply disruption.

This leads to a reduction in fat mass and improved metabolic biomarkers like insulin sensitivity, making Adipotide a subject of great interest in obesity, diabetes, and fat metabolism studies.

Research Applications of Adipotide:

1. Obesity and Weight Loss Research